181 research outputs found

    SYCL compute kernels for ExaHyPE

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    We discuss three SYCL realisations of a simple Finite Volume scheme over multiple Cartesian patches. The realisation flavours differ in the way how they map the compute steps onto loops and tasks: We compare an implementation which is exclusively using a cascade of for-loops to a version which uses nested parallelism, and finally benchmark these against a version which models the calculations as task graph. Our work proposes realisation idioms to realise these flavours within SYCL. The idioms translate to some degree to other GPGPU programming techniques, too. Our preliminary results suggest that SYCL's capability to model calculations via tasks or nested parallelism does not yet allow such realisations to outperform their counterparts using exclusively data parallelism

    SYCL compute kernels for ExaHyPE *

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    We discuss three SYCL realisations of a simple Finite Volume scheme over multiple Cartesian patches. The realisation flavours differ in the way how they map the compute steps onto loops and tasks: We compare an implementation that is exclusively using a sequence of for-loops to a version that uses nested parallelism, and finally benchmark these against a version modelling the calculations as task graph. Our work proposes realisation idioms to realise these flavours within SYCL. The results suggest that a mixture of classic task and data parallelism performs if we map this hybrid onto a solely data-parallel SYCL implementation, taking into account SYCL specifics and the problem size

    Neurocognitive function, performance status, and quality of life in pediatric intracranial germ cell tumor survivors

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    Background: Intracranial germ cell tumors (GCT) are more common in Asia than in the West, accounting for about 15% of brain tumors in Asian children. The survival rate for intracranial GCT is excellent, but there are concerns about the effects of radiotherapy on neuropsychological function and quality of life of patients. Methods: Intracranial germ cell tumors (GCT) are more common in Asia than in the West, accounting for about 15% of brain tumors in Asian children. The survival rate for intracranial GCT is excellent, but there are concerns about the effects of radiotherapy on neuropsychological function and quality of life of patients. Intracranial GCT survivors in Hong Kong aged ≄ 6 years who received cranial irradiation in the past 15 years were recruited. Neurocognitive function and performance status were assessed by the Hong Kong Wechsler Intelligence scale and Karnofsky/Lansky performance scales (KPS), respectively. Quality of life was assessed using the Pediatric Quality of Life Inventory (PedsQL) Generic Core Scales. A chart review was performed for tumor characteristics and complications related to the tumor and its treatment. Results: Twenty-five intracranial GCT survivors were recruited. Longer length of time since treatment was associated with lower IQ scores. Larger tumor size was associated with lower KPS scores. Hemiparesis, poor manual dexterity, and complications with multi-organ involvement were associated with significantly lower KPS scores. Higher irradiation dosage was associated with lower PedsQL physical scores. Conclusions: The majority of GCT survivors had average intellectual functioning, satisfactory performance status and relatively good quality of life, except in the physical aspect. Comprehensive evaluation and long-term follow-up of GCT survivors are essential to provide timely support and improve long-term outcomes

    Trastuzumab Deruxtecan versus Trastuzumab Emtansine for Breast Cancer

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    Observation of Several Sources of CPCP Violation in B+→π+π+π−B^+ \to \pi^+ \pi^+ \pi^- Decays

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    International audienceObservations are reported of different sources of CP violation from an amplitude analysis of B+→π+π+π- decays, based on a data sample corresponding to an integrated luminosity of 3  fb-1 of pp collisions recorded with the LHCb detector. A large CP asymmetry is observed in the decay amplitude involving the tensor f2(1270) resonance, and in addition significant CP violation is found in the π+π-S wave at low invariant mass. The presence of CP violation related to interference between the π+π-S wave and the P wave B+→ρ(770)0π+ amplitude is also established; this causes large local asymmetries but cancels when integrated over the phase space of the decay. The results provide both qualitative and quantitative new insights into CP -violation effects in hadronic B decays

    Amplitude analysis of the B(s)0→K∗0K‟∗0B^0_{(s)} \to K^{*0} \overline{K}^{*0} decays and measurement of the branching fraction of the B0→K∗0K‟∗0B^0 \to K^{*0} \overline{K}^{*0} decay

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    International audienceThe B0→K∗0K‟∗0 {B}^0\to {K}^{\ast 0}{\overline{K}}^{\ast 0} and Bs0→K∗0K‟∗0 {B}_s^0\to {K}^{\ast 0}{\overline{K}}^{\ast 0} decays are studied using proton-proton collision data corresponding to an integrated luminosity of 3 fb−1^{−1}. An untagged and timeintegrated amplitude analysis of B_{( s}_{)}^{0}  → (K+^{+}π−^{−})(K−^{−}π+^{+}) decays in two-body invariant mass regions of 150 MeV/c2^{2} around the K∗0^{∗0} mass is performed. A stronger longitudinal polarisation fraction in the B0→K∗0K‟∗0 {B}^0\to {K}^{\ast 0}{\overline{K}}^{\ast 0} decay, fL_{L} = 0.724 ± 0.051 (stat) ± 0.016 (syst), is observed as compared to fL_{L} = 0.240 ± 0.031 (stat) ± 0.025 (syst) in the Bs0→K∗0K‟∗0 {B}_s^0\to {K}^{\ast 0}{\overline{K}}^{\ast 0} decay. The ratio of branching fractions of the two decays is measured and used to determine B(B0→K∗0K‟∗0)=(8.0±0.9(stat)±0.4(syst))×10−7 \mathrm{\mathcal{B}}\left({B}^0\to {K}^{\ast 0}{\overline{K}}^{\ast 0}\right)=\left(8.0\pm 0.9\left(\mathrm{stat}\right)\pm 0.4\left(\mathrm{syst}\right)\right)\times {10}^{-7}
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